(Lys²²)-Amyloid β-Protein (1-40)

CAS: 302905-01-7

Rif. 01-4049003

Informazioni sul prodotto

• Nome: (Lys²²)-Amyloid β-Protein (1-40)
• Sinonimi: Amyloid β-Protein (1-40) Italian Mutation
• Marchio: Bachem
• Descrizione: The Italian mutation of β-amyloid 1-40 (E22K) aggregates more rapidly than the wild-type sequence 1-40. It showed increased neurotoxicity, which (according to a solid-phase NMR-study of Masuda et al.) may be due to the salt bridge formed between Lys²² and Asp²³ in the minor conformer. As the Arctic, Flemish, and Dutch mutants, the Italian mutant is degraded considerably more slowly than wild-type Aβ by neprilysin.

Proprietà chimiche

• Peso molecolare: 4328.92
• Formula: C₁₉₅H₃₀₀N₅₄O₅₆S
• Purezza: 91.3%
• Colore/Forma: White Lyophilisate