Tamoxifen citrate

CAS: 54965-24-1

Rif. 02-J60955

Informazioni sul prodotto

• Nome: Tamoxifen citrate
• Sinonimi: cis-1-(4-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene citrate, (Z)-2-[4-(1,2-Diphenyl-1-Butenyl)Phenoxyl]-N,N-Dimethyl-Ethanamine-Citrate, 1-P-Beta-Dimethylaminoethoxyphenyl-Trans-1,2-Diphenylbut-1-Ene Citrate, 2-{4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (salt), Ethanamine, 2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (Z)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1), Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1), Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1), Genox, I.C.I.46474 citrate, Ici 46474, Istubal, Kessar, Noltam, Nolvadex, Nourytam, Soltamox, Tamofen, Tamoplex, Tamox-Puren, Tamoxiphen Citrate, Tomaxasta, Valodex, Z-Tamoxifen citrate, Zemide

Descrizione

Tamoxifen citrate is used as an antiestrogen with potent anti-cancer and PKC inhibitory activities. Tamoxifen Citrate functions as an estrogen receptor antagonist in breast tissue. Tamoxifen Citrate is an agonist towards this receptor in tissues of the endometrium. Tamoxifen Citrate inhibits DNA synthesis and transcription by recruiting co-repressors, which stop estrogen from interacting with genes. When combined with PAX2, Tamoxifen Citrate can inhibit the proliferation of ERBB2. It is also a high affinity activator of the GPR30 receptor. Tamoxifen Citrate is an activator of Estrogen Receptor. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Marchio: Alfa Aesar By Thermo Fisher Scientific

Proprietà chimiche

• Peso molecolare: 563.65
• Formula: C₂₆H₂₉NO·C₆H₈O₇