KYL
CAS: 676657-00-4
Rif. 3D-BCB65700
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Informazioni sul prodotto
KYL is a cyclic peptide that has been shown to bind to the MT2 receptor and inhibit its activity. This receptor regulates axonal growth, and KYL is an antagonist of this receptor. The physiological function of the MT2 receptor is not known. KYL inhibits prostate cancer cells by binding to their receptors. KYL was also shown to inhibit skin cancer in vivo, which may be due to its ability to inhibit protein synthesis and cell division in these cells. Structural analysis showed that KYL binds tightly with nitrogen atoms on the surface of the MT2 receptor, which may account for its high affinity for the receptor. The affinity of KYL for the MT2 receptor can be increased by changing its structure through chemical modification. In vitro studies have shown that KYL inhibits granule neuron production in rats by binding to a different site on the MT2 receptor than it does in prostate cancer cells or skin cancer cells. Titration calorimetry revealed that KYL binds weakly with
Proprietà chimiche
Richiesta tecnica su: 3D-BCB65700 KYL
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