(R)-3,4-DCPG
CAS: 201730-10-1
Rif. 3D-BIA73010
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Informazioni sul prodotto
(R)-3,4-DCPG is a metabotropic glutamate receptor agonist that has been shown to have potentiating effects in the brain. It is expressed in the cerebral cortex and has been shown to be effective against epilepsy. (R)-3,4-DCPG has been shown to act as an agonist of the mGlu2 receptor and is used as a model drug for studying this receptor. It binds to the mGlu2 receptor with high affinity and potentiates its activity by increasing calcium influx into neurons. This leads to increased activation of second messenger systems, such as phospholipase C, which then causes a cascade of events leading to the release of glutamate from presynaptic terminals. This potentiation leads to an increase in stimulation of postsynaptic receptors and an increase in neuronal excitability.
Proprietà chimiche
Richiesta tecnica su: 3D-BIA73010 (R)-3,4-DCPG
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