RO-9187
CAS: 876708-03-1
Rif. 3D-BKB70803
| 1mg | 348,00 € | ||
| 5mg | 501,00 € | ||
| 10mg | 713,00 € | ||
| 25mg | 1.199,00 € | ||
| 50mg | 1.918,00 € |
Informazioni sul prodotto
- 2(1H)-Pyrimidinone, 4-amino-1-(4-C-azido-β-D-arabinofuranosyl)-
- RO 9187
- 4-Amino-1-(4-C-azido-β-D-arabinofuranosyl)-2(1H)-pyrimidinone
- 2′-Deoxy-2′-beta-hydroxy-4′-azidocytidine
RO-9187 is a modified oligonucleotide that inhibits the replication and spread of hepatitis B virus. It is a nucleoside analog with a deoxycytidine kinase-inhibiting activity. RO-9187 has shown antiviral activity in vitro and in vivo against the cell culture-grown hepatitis B virus, as well as against other viruses such as HIV and herpes simplex virus. The drug is pegylated to increase its plasma half-life and reduce renal clearance, making it more suitable for chronic use. RO-9187 has been shown to be active against viral strains that are resistant to other nucleosides analogs, including lamivudine, adefovir dipivoxil, entecavir, and telbivudine.
Proprietà chimiche
Richiesta tecnica su: 3D-BKB70803 RO-9187
Se si desidera richiedere un preventivo o effettuare un ordine, si prega invece di aggiungere i prodotti desiderati al carrello e poi richiedere un preventivo o un ordine dal carrello. È più veloce, più economico, e potrà beneficiare degli sconti disponibili e di altri vantaggi.
