Ispronicline
CAS: 252870-53-4
Rif. 3D-CKA87053
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Informazioni sul prodotto
- (2S,4E)-N-Methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine
- (2S,4E)-N-Methyl-5-[5-(1-methylethoxy)-3-pyridinyl]-4-penten-2-amine
- TC 01734
- 4-Penten-2-amine, N-methyl-5-[5-(1-methylethoxy)-3-pyridinyl]-, (2S,4E)-
Ispronicline is a nicotinic acetylcholine receptor (nAChR) agonist that binds to the α7-nAChR subtype. It has been shown to reduce the symptoms of cancer, such as depression and anxiety, by increasing the release of neurotrophic factors. Ispronicline may also be used in combination with other drugs, such as dimethyl fumarate or acetylcholinesterase inhibitors, for the treatment of neurodegenerative disorders. Ispronicline binds to nAChRs on central nervous system neurons and peripheral nerves. This binding enhances neurotransmitter release from nerve endings, which stimulates nicotinic receptors on adjacent cells, leading to an increased release of dopamine. Ispronicline has a terminal half-life of about 2 hours and is metabolized by CYP3A4 enzymes in the liver. Metformin hydrochloride can inhibit CYP3A4 enzyme activity and increase blood levels of is
Proprietà chimiche
Richiesta tecnica su: 3D-CKA87053 Ispronicline
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