1-Chloro-6-(5-(prop-1-ynyl)thiophen-2-yl)hexa-3,5-diyn-2-ol
CAS: 78876-52-5
Rif. 3D-DDA87652
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Informazioni sul prodotto
Pterocaulon is a natural product with an unknown mechanism of action. It has been shown to be effective against organisms such as Gram-positive bacteria and fungi, but not against Gram-negative bacteria. Pterocaulon has been shown to inhibit bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Pterocaulon also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.
Proprietà chimiche
Richiesta tecnica su: 3D-DDA87652 1-Chloro-6-(5-(prop-1-ynyl)thiophen-2-yl)hexa-3,5-diyn-2-ol
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