ABT 737

CAS: 852808-04-9

Rif. 3D-FA16902

Informazioni sul prodotto

• Nome: ABT 737
• Sinonimi: 4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nit rophenyl]sulfonyl]benzamide
• Marchio: Biosynth
• Descrizione: Inhibits anti-apoptotic proteins Bcl-2, Bcl-xl and Bcl-w. Synergistic with chemotherapy and radiotherapy in several tumour cell lines. Potent activity as a single agent in lymphoid cancer and small cell lung cancer (SCLC) cell lines. Causes tumour regression in SCLC xenograft tumour in vivo.

Proprietà chimiche

• Peso molecolare: 813.43 g/mol
• Formula: C₄₂H₄₅ClN₆O₅S₂
• Purezza: Min. 95%
• Colore/Forma: Yellow Solid