N-Acetyl sulfamethoxazole

CAS: 21312-10-7

Rif. 3D-FA17046

Informazioni sul prodotto

• Nome: N-Acetyl sulfamethoxazole
• Sinonimi: N-[4-[[(5-Methyl-3-isoxazolyl)amino]sulfonyl]phenyl]acetamide4'-Acetyl-3-sulfa-5-methylisoxazoleN4-Acetylsulfamethoxazole, 4′-Acetyl-3-sulfa-5-methylisoxazole, Acetamide, N-[4-[[(5-methyl-3-isoxazolyl)amino]sulfonyl]phenyl]-, Acetanilide, 4′-[(5-methyl-3-isoxazolyl)sulfamoyl]-, Acetylsulfamethoxazole, N-Acetylsulfamethoxazole, N-[4-[[(5-Methyl-3-isoxazolyl)amino]sulfonyl]phenyl]acetamide, N-{4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]phenyl}acetamide, N4-Acetylsulfamethoxazole, N₄-Acetylsulfamethoxazole, N⁴-Acetylsulfamethoxazole, N⁴-Acetylsulfisomezole, Stx 606, Sulfisomezole-N⁴-acetate, Sulfisomezole-N4-acetate, N4-Acetylsulfisomezole

Descrizione

N-Acetyl sulfamethoxazole is a sulfa drug that inhibits bacterial growth by inhibiting the production of folic acid. N-Acetyl sulfamethoxazole can be used for the treatment of infectious diseases, such as pneumonia and bronchitis. It has been shown to reduce the incidence of urinary tract infections caused by Escherichia coli and other bacteria. This drug is metabolized in humans through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. N-Acetyl sulfamethoxazole also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 295.32 g/mol
• Formula: C₁₂H₁₃N₃O₄S
• Purezza: Min. 95%
• InChI: InChI=1S/C12H13N3O4S/c1-8-7-12(14-19-8)15-20(17,18)11-5-3-10(4-6-11)13-9(2)16/h3-7H,1-2H3,(H,13,16)(H,14,15)
• InChI key: InChIKey=GXPIUNZCALHVBA-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1ccc(S(=O)(=O)Nc2cc(C)on2)cc1