Informazioni sul prodotto
- Pyrazolo[1,5-a]pyrimidine-6-carboxamide, N-[2-[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]-2-methylpropyl]-2-methyl-
- N-[2-([2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide
- Suiny
- N-[2-[[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide
Anagliptin is a dipeptidyl peptidase-4 inhibitor that is used in combination with insulin to treat type 2 diabetes. It has been shown to reduce postprandial blood glucose levels and improve the quality of life for patients with type 2 diabetes. Anagliptin inhibits DPP-IV, which helps regulate blood glucose levels by breaking down proinsulin into insulin. This drug also has anti-inflammatory properties, which may be due to its inhibition of the apoptosis pathway in an injury model system. Anagliptin, when combined with dextran sulfate, can be used as an agent for preventing atherosclerotic lesions in rabbits. The molecular docking analysis revealed that this drug binds to the hydrophobic pocket at the active site of DPP-IV, inhibiting its activity and lowering blood glucose levels.
Proprietà chimiche
Richiesta tecnica su: 3D-FA31542 Anagliptin
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