4'-Bromomethyl-2-biphenylcarbonitrile

CAS: 114772-54-2

Rif. 3D-FB07707

Informazioni sul prodotto

• Nome: 4'-Bromomethyl-2-biphenylcarbonitrile
• Sinonimi: 2-(4-Bromo-Methylphenyl) Benzonitrile, 2-(4-Bromomethylphenyl)benzonitrile, 2-Cyamo-4'-bromo methylbiphenyl, 2-Cyano-4'-Bromomethyl Biphenyl, 2-Cyano-4'-bromomethyl Diphenyl, 2-Cyano-4-Bromomethylbiphenyl, 2′-(Cyano)biphenyl-4-ylmethyl bromide, 2′-Cyano-4-(bromomethyl)-1,1′-biphenyl, 4'-Bromomethyl-2-Cyano Biphenyl, 4'-Bromomethylbiphenyl-2-Carbonitrile, 4-(2-Cyanophenyl)benzyl bromide, 4-Bromomethyl-2-Biphenylcarbonitrile, 4-Bromomethyl-2′-cyano-1,1′-biphenyl, 4′-(Bromomethyl)[1,1′-biphenyl]-2-carbonitrile, Br-OTBN, Bromoethylcyanobiphenyl, Otbnbr, [1,1'-Biphenyl]-2-Carbonitrile, 4'-(Bromomethyl)-

Descrizione

4'-Bromomethyl-2-biphenylcarbonitrile is an impurity in certain medicines that has been detected in the form of a yellow crystal. It is a byproduct of the reaction between dibutyltin oxide and imidazole hydrochloride. 4'-Bromomethyl-2-biphenylcarbonitrile has been found to be present in azilsartan, a medicine used for high blood pressure, but it is not known if this impurity will affect the therapeutic efficacy of this drug. The presence of this impurity may be due to its selective reactivity with hydrocarbon solvents and carboxylic acids. The functional theory suggests that 4'-Bromomethyl-2-biphenylcarbonitrile is formed when there are functional groups on the starting material (such as carboxylic acid) which can bind to bromine atoms via an electrophilic substitution reaction.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 272.14 g/mol
• Formula: C₁₄H₁₀BrN
• Purezza: Min. 95%
• Colore/Forma: Powder
• InChI: InChI=1S/H3N/h1H3
• InChI key: InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
• SMILES: N#Cc1ccccc1-c1ccc(CBr)cc1