8-Benzyloxy- 5-(2-bromoacetyl)-2(1H)-quinolinone

CAS: 100331-89-3

Rif. 3D-FB18407

Informazioni sul prodotto

• Nome: 8-Benzyloxy- 5-(2-bromoacetyl)-2(1H)-quinolinone
• Sinonimi: 5-(Bromoacetyl)-8-(phenylmethoxy)-2(1H)-quinolinone5-(2-Bromo-1-oxoethyl)-8-benzyloxy-2(1H)-quinolinone5-Bromoacetyl-8-benzyloxyca rbostyril, 1-[8-(Benzyloxy)-2-hydroxyquinolin-5-yl]-2-bromoethanone, 2(1H)-Quinolinone, 5-(2-bromoacetyl)-8-(phenylmethoxy)-, 8-(Benzyloxy)-5-(bromoacetyl)quinolin-2(1H)-one, Ethanone, 2-Bromo-1-[2-Hydroxy-8-(Phenylmethoxy)-5-Quinolinyl]-, 8-benzyloxy-5-(2-bromoacetyl)-2-(1H)-quinolinone, 8-Benzyloxy-5-(2-bromoacetyl)-2-(1h)-quinoline

Descrizione

8-Benzyloxy-5-(2-bromoacetyl)-2(1H)-quinolinone (BQ) is a phosphine ligand that has been used in industrial applications. It is also used to synthesize indacaterol maleate, which is a drug for the treatment of chronic obstructive pulmonary disease. The reduction reaction of BQ by hydroxide ions produces indacaterol, which is then catalyzed by maleic acid to form indacaterol maleate. This drug has been shown to be effective in the treatment of chronic obstructive pulmonary diseases and asthma. The chirality of BQ can be changed by adding a chiral ligand such as (R)- or (S)-borane to provide the desired stereochemistry.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 372.21 g/mol
• Formula: C₁₈H₁₄BrNO₃
• Purezza: Min. 95%
• InChI: InChI=1S/C18H14BrNO3/c19-10-15(21)13-6-8-16(18-14(13)7-9-17(22)20-18)23-11-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,20,22)
• InChI key: InChIKey=RVHSDLUBNZBRMH-UHFFFAOYSA-N
• SMILES: O=C(CBr)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12