4-Bromoindazole
CAS: 186407-74-9
Rif. 3D-FB29052
| 10g | 58,00 € | ||
| 25g | 108,00 € | ||
| 50g | 180,00 € | ||
| 100g | 271,00 € | ||
| 250g | 533,00 € |
Informazioni sul prodotto
4-Bromoindazole is an antibacterial agent that binds to the protonated form of the staphylococcal enzyme methicillin-resistant penicillinase (MRP) and prevents the enzyme from participating in the synthesis of cell wall precursors. The molecular modeling studies of 4-bromoindazole have shown that it can bind to pyogenes, a bacterium that causes streptococcal pharyngitis, by hydrogen bonding between its amide group and pyogenes' carboxylic acid group. 4-Bromoindazole also has anticancer activity against cancer cells with v600e mutation. It has been shown that 4-bromoindazole inhibits cancer cell proliferation by binding to the oxacillin site on DNA gyrase and topoisomerase IV, leading to DNA damage and apoptosis.
Proprietà chimiche
Richiesta tecnica su: 3D-FB29052 4-Bromoindazole
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