1-Benzoylpiperazine
CAS: 13754-38-6
Rif. 3D-FB37816
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| 25g | Prezzo su richiesta |
Informazioni sul prodotto
- Chembrdg-Bb 5108505
- Akos Bb-6352
- Phenyl-Piperazin-1-Yl-Methanone
- N-Benzoylpiperazine
- 1-Benzoyl-Piperazine
- 1-Benzotriazolemonhydate Chem-4170
- 4-(Phenylcarbonyl)Piperazin-1-Ium
1-Benzoylpiperazine is a prodrug that is converted by esterases to its active form, 1-benzylpiperazine. It has been shown to have potent inhibitory activity against the growth of human cancer cells and was found to be more potent than piperazine in vitro. A molecular modeling study revealed that 1-benzoylpiperazine binds to the active site of monoacylglycerol lipase (MAGL) with high affinity and inhibits its enzymatic activity. The binding site for 1-benzoylpiperazine on MAGL is different from that of other inhibitors, such as phenylbutazone or indomethacin. The activation energies for 1-benzoylpiperazine binding were calculated using thermodynamic parameters derived from nmr spectra and are reported in kcal/mol.
Proprietà chimiche
Richiesta tecnica su: 3D-FB37816 1-Benzoylpiperazine
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