5-Bromo-1H-indazole

Rif. 3D-FB50830

Informazioni sul prodotto

• Nome: 5-Bromo-1H-indazole
• Sinonimi: 5-Bromoindazole
• Marchio: Biosynth
• Descrizione: 5-Bromo-1H-indazole is an indazole derivative that has been shown to have potential use in the treatment of pain. It binds to the allosteric site on the enzyme gyrase, which is a DNA topoisomerase that controls the supercoiling of DNA. This binding prevents ATP from binding and inhibits DNA unwinding, leading to a decrease in DNA synthesis and cell division. 5-Bromo-1H-indazole also binds with high affinity at the allosteric site on the enzyme adenylate cyclase, which is involved in signal transduction pathways. Binding of 5-bromo-1H-indazole causes an increase in cAMP levels and leads to functional effects such as antinociception.

Proprietà chimiche

• Peso molecolare: 197.03 g/mol
• Formula: C₇H₅BrN₂
• Purezza: Min. 95%
• InChI: InChI=1S/C7H5BrN2/c8-6-1-2-7-5(3-6)4-9-10-7/h1-4H,(H,9,10)
• InChI key: InChIKey=STVHMYNPQCLUNJ-UHFFFAOYSA-N
• SMILES: Brc1ccc2[nH]ncc2c1