4-Bromo-2-fluoro-N-methylbenzamide

CAS: 749927-69-3

Rif. 3D-FB81945

Informazioni sul prodotto

• Nome: 4-Bromo-2-fluoro-N-methylbenzamide
• Sinonimi: 4-Bromo-2-fluoro-N-methyl-benzamide, N-methyl-4-bromo-2-fluorobenzamide

Descrizione

4-Bromo-2-fluoro-N-methylbenzamide is an impurity in the pharmaceutical drug nilutamide. It is a ligand that binds to the androgen receptor and inhibits the binding of dihydrotestosterone, reducing its effect on prostate cells. 4-Bromo-2-fluoro-N-methylbenzamide has been shown to have pharmacokinetic properties similar to nilutamide, which is a drug used for treating prostate cancer. This impurity is also found in small quantities in other drugs including cyclobutanone, 2-aminoisobutyric acid, and chloral hydrate. The elucidation of these impurities can help regulate the quality of pharmaceutical drugs.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 232.05 g/mol
• Formula: C₈H₇BrFNO
• Purezza: Min. 95%
• Colore/Forma: White Off-White Powder
• InChI: InChI=1S/C8H7BrFNO/c1-11-8(12)6-3-2-5(9)4-7(6)10/h2-4H,1H3,(H,11,12)
• InChI key: InChIKey=BAJCFNRLEJHPTQ-UHFFFAOYSA-N
• SMILES: CNC(=O)c1ccc(Br)cc1F