
Cyclopropanesulfonyl chloride
CAS:
Rif. 3D-FC52987

Informazioni sul prodotto
- Chlorocyclopropylsulfone Cyclopropylsulfonyl chloride
Cyclopropanesulfonyl chloride (CPSC) is a bicyclic heterocycle that has been shown to have potent inhibitory activity against the human pathogens hepatitis B virus, dengue virus, and influenza A virus. CPSC inhibits the NS3 protease of these viruses by forming hydrogen bonding interactions with the nucleophilic nitrogen atom of the enzyme and also by competing with a chloride ion for binding to the chlorine atom on the enzyme. It also inhibits HIV-1 infection in cell culture experiments. CPSC has been found to be effective in preventing inflammation caused by cytokines, such as interleukin-1β, tumor necrosis factor-α, and prostaglandin E2. The inhibition of inflammatory cytokines may be due to its ability to bind glucocorticoid receptors.
Proprietà chimiche
Richiesta tecnica su: Cyclopropanesulfonyl chloride
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