3a,21-Dihydroxy-5a-pregnane-11,20-dione 21-acetate
CAS: 23930-37-2
Rif. 3D-FD158987
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Informazioni sul prodotto
- (3-alpha,5-alpha)-21-(Acetyloxy)-3-hydroxypregnane-11,20-dione
- (3Alpha,5Alpha)-3-Hydroxy-11,20-Dioxopregnan-21-Yl Acetate
- (3α,5α)-21-(Acetyloxy)-3-hydroxypregnane-11,20-dione
- (3α,5α)-3-Hydroxy-11,20-dioxopregnan-21-yl acetate
- 21-Acetoxy-3-alpha-hydroxy-5-alpha-pregnane-11,20-dione
- 21-Acetoxy-3α-hydroxy-5α-pregnane-11,20-dione
- 3-Hydroxy-11,20-Dioxopregnan-21-Yl Acetate
- 3alpha,21-Dihydroxy-5alpha-pregnane-11,20-dione 21-acetate
- 5-alpha-Pregnane-11,20-dione, 3-alpha,21-dihydroxy-, 21-acetate
- 5α-Pregnane-11,20-dione, 3α,21-dihydroxy-, 21-acetate
- Vedi altri sinonimi
- Alfadolone acetate
- Alphadolone acetate
- Gr 2/1574
- Pregnane-11,20-dione, 21-(acetyloxy)-3-hydroxy-, (3-alpha,5-alpha)-
- Pregnane-11,20-dione, 21-(acetyloxy)-3-hydroxy-, (3α,5α)-
- Unii-00Tn4Gs00S
3a,21-Dihydroxy-5a-pregnane-11,20-dione 21-acetate is a short-acting intravenous anaesthetic that is used in surgical procedures. It has been shown to have antinociceptive properties and can be used as a potent analgesic. 3a,21-Dihydroxy-5a-pregnane-11,20-dione 21-acetate binds to the alpha1 adrenergic receptor and blocks the release of noradrenaline from nerve terminals in the brain. This prevents the activation of neurons in the spinal cord that transmit pain signals to the brain. The drug also inhibits the action of gamma aminobutyric acid on neurones and increases levels of cortisol concentration in blood plasma. The mechanism by which 3a,21 -dihydroxy 5a pregnane 11,20 dione 21 acetate produces its anaesthetic effects has not yet been elucidated.
Proprietà chimiche
Richiesta tecnica su: 3D-FD158987 3a,21-Dihydroxy-5a-pregnane-11,20-dione 21-acetate
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