Fmoc-L-cyclohexylglycine
CAS: 161321-36-4
Rif. 3D-FF55893
| 5g | Fuori produzione | ||
| 10g | Fuori produzione | ||
| 25g | Fuori produzione | ||
| 50g | Fuori produzione | ||
| 100g | Fuori produzione |
Informazioni sul prodotto
Nome:
Fmoc-L-cyclohexylglycine
Sinonimi:
- Fmoc-L-Chg-OHFmoc-cyclohexyl-Gly-OH
- Fmoc-Chg-OH
- Fmoc-L-Cyclohexyl glycine
- Cyclohexaneaceticacid, a-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (aS)-
- Cyclohexaneaceticacid, a-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (S)-
- (2S)-2-Cyclohexyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)acetic acid
Descrizione:
Fmoc-L-cyclohexylglycine is a potent inhibitor of the NS3 protease. It constitutes one of the first anti-hepatitis C virus (HCV) inhibitors that are potent and selective. The drug has been shown to inhibit HCV replication in vitro with low nanomolar potency and high selectivity. Fmoc-L-cyclohexylglycine is a trisubstituted cyclopentane, which binds to an active site on the NS3 protease and blocks the enzyme's catalytic activity. Fmoc-L-cyclohexylglycine also inhibits other proteases, such as HIV protease and influenza virus NS1 proteinase, by binding to a template region within their active sites.
Avviso:
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Marchio:
Biosynth
Conservazione lunga:
Note:
Proprietà chimiche
Peso molecolare:
379.45 g/mol
Formula:
C23H25NO4
Purezza:
Min. 95%
InChI:
InChI=1S/C23H25NO4/c25-22(26)21(15-8-2-1-3-9-15)24-23(27)28-14-20-18-12-6-4-10-16(18)17-11-5-7-13-19(17)20/h4-7,10-13,15,20-21H,1-3,8-9,14H2,(H,24,27)(H,25,26)/t21-/m0/s1
InChI key:
InChIKey=BWQQGHPODCJZDB-NRFANRHFSA-N
SMILES:
O=C(N[C@H](C(=O)O)C1CCCCC1)OCC1c2ccccc2-c2ccccc21
MDL:
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