Fmoc-L-cyclohexylglycine

CAS: 161321-36-4

Rif. 3D-FF55893

Informazioni sul prodotto

• Nome: Fmoc-L-cyclohexylglycine
• Sinonimi: Fmoc-L-Chg-OHFmoc-cyclohexyl-Gly-OH, Fmoc-Chg-OH, Fmoc-L-Cyclohexyl glycine, Cyclohexaneaceticacid, a-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (aS)-, Cyclohexaneaceticacid, a-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (S)-, (2S)-2-Cyclohexyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)acetic acid

Descrizione

Fmoc-L-cyclohexylglycine is a potent inhibitor of the NS3 protease. It constitutes one of the first anti-hepatitis C virus (HCV) inhibitors that are potent and selective. The drug has been shown to inhibit HCV replication in vitro with low nanomolar potency and high selectivity. Fmoc-L-cyclohexylglycine is a trisubstituted cyclopentane, which binds to an active site on the NS3 protease and blocks the enzyme's catalytic activity. Fmoc-L-cyclohexylglycine also inhibits other proteases, such as HIV protease and influenza virus NS1 proteinase, by binding to a template region within their active sites.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 379.45 g/mol
• Formula: C₂₃H₂₅NO₄
• Purezza: Min. 95%
• InChI: InChI=1S/C23H25NO4/c25-22(26)21(15-8-2-1-3-9-15)24-23(27)28-14-20-18-12-6-4-10-16(18)17-11-5-7-13-19(17)20/h4-7,10-13,15,20-21H,1-3,8-9,14H2,(H,24,27)(H,25,26)/t21-/m0/s1
• InChI key: InChIKey=BWQQGHPODCJZDB-NRFANRHFSA-N
• SMILES: O=C(N[C@H](C(=O)O)C1CCCCC1)OCC1c2ccccc2-c2ccccc21