3D-FF82399 - 3-4-fluorobenzyloxybenzaldehyde | 168084-96-6

Applications 3-Benzyloxybenzaldehyde-alpha-d1 (CAS# 1219805-34-1) is a useful isotopically labeled research compound.

Applications 4-Benzyloxybenzaldehyde is a position isomer of the adenylyl cyclase activator 2-Benzyloxybenzaldehyde. 4-Benzyloxybenzaldehyde also has much less potent anticancer activity against HL-60 cells that its isomeric counterpart.
References Lin, C. et al.: Bioorg. Med. Chem., 13, 1537 (2005); Chang, C.-Y. et al.: Bioorg. Med. Chem. Lett., 11, 1971 (2001);

4-Benzyloxybenzaldehyde is a molecule with an aldehyde group and a benzyl alcohol group. It is the most active inhibitor of Candida glabrata among the compounds tested. 4-Benzyloxybenzaldehyde has been shown to inhibit Candida glabrata, Propionibacterium acnes, and Pseudomonas aeruginosa. This compound also inhibits hydrogen chloride production by Candida glabrata in vitro. 4-Benzyloxybenzaldehyde inhibits Candida glabrata by binding to the enzyme hydrogenase at the alpha-subunit's active site to prevent its function.
4-Benzyloxybenzaldehyde has been found to be more potent than benzoic acid in inhibiting candida growth, although less potent than gentamicin or erythromycin.