3D-FF85869 - 3-fluorophenyl4-piperidinylmethanone | 639468-63-6

Applications An intermediate in the preparation of serotonin 5-HT2a receptor antagonists
References Ullrich, T., et al.: Bioorg. Med. Chem., 8, 2427 (2000),

Applications (4-Chlorophenyl)-4-piperidinylmethanone Hydrochloride (cas# 55695-51-7) is a compound useful in organic synthesis.

Applications An intermediate in the preparation of serotonin 5-HT2a receptor antagonists
References Nambu, K., et al.: Biochem. Pharmacol., 36, 1715 (1987), Hansch, C., et al.: Biopharm., 5, 129 (1990),

1. Activates TRPV1 receptor, which is involved in the transmission of pain signals and the release of inflammatory mediators
2. Binds to and activates P2X7 receptors, which are associated with cell death and inflammation
3. Blocks voltage-gated calcium channels, which play a role in neuronal excitability and muscle contraction
4. Inhibits the activity of MAP kinase phosphatases, which are involved in regulating the activation of MAP kinase
5. Stimulates ligand-gated ion channels such as nicotinic acetylcholine receptors (nAChRs)
6. Binds to GABA receptors, inhibiting the effects of GABA on neurons
7. Acts as an antagonist at dopamine D2 receptors
8. Binds to muscarinic M1/M3 receptors, inhibiting acetylcholine release
9. Binds to alpha-adrenergic receptors, leading to vas

Applications 1,1'-Carbonyldipiperidine is a urea.
References Betz, R., et al.: Acta Crystallogr. Section E., 67, 397 (2011); De Souza, H. K. S., et al.: J. Solid State Chem., 171, 242 (2003); Li, C., et al.: J. Med. Chem., 24, 1089 (1981)

Applications Risperidone intermediate.