Gnidimacrin

CAS: 60796-70-5

Rif. 3D-FG158061

Informazioni sul prodotto

• Nome: Gnidimacrin
• Sinonimi: 16aH-1,6:2,6-Diepoxybenz[7,8]oxireno[5,6]azuleno[8,1-bc]oxacyclotridecin-7,16,16a,17-tetrol, 4-[(benzoyloxy)methyl]eicosahydro-17a-(hydroxymethyl)-14,15-dimethyl-2-(1-methylethenyl)-, 16-benzoate, (1R,2R,4S,4aR,6S,7R,14R,14aS,15S,16S,16aS,16bR,17S,17aR,18aS,18bS)-, 16aH-1,6:2,6-Diepoxybenz[7,8]oxireno[5,6]azuleno[8,1-bc]oxacyclotridecin-7,16,16a,17-tetrol, 4-[(benzoyloxy)methyl]eicosahydro-17a-(hydroxymethyl)-14,15-dimethyl-2-(1-methylethenyl)-, 16-benzoate, [1R-(1R*,2R*,4S*,4aR*,6S*,7R*,14R*,14aS*,15S*,16S*,16aS*,16bR*,17S*,17aR*,18aS*,18bS*)]-, Ligustrinin b, [1R-(1R*,2R*,4S*,4aR*,6S*,7R*,14R*,14aS*,15S*,16S*,16aS*,16bR*,17S*,17aR*,18aS*,18bS*)]-4-[(Benzoyloxy)methyl]eicosahydro-7,16a,17-trihydroxy-17a-(hydroxymethyl)-14,15-dimethyl-2-(1-methylethenyl)-2H-1,6:2,6-diepoxybenz[7,8]oxireno[5,6]azuleno[8,1-bc]oxacyclotridecin-16-yl benzoate

Descrizione

Gnidimacrin is an active, orally bioavailable small molecule that has been shown to be effective as an antiretroviral therapy. It has been shown to inhibit HIV infection by blocking the binding of HIV-1 gp120 to its receptor CD4, which is required for viral entry into the host cell. Gnidimacrin also inhibits the production of proinflammatory cytokines and neurotrophic factors, such as tumor necrosis factor and epidermal growth factor. This drug also has antiviral activity against human cytomegalovirus (HCMV) and herpes simplex virus type 1 (HSV-1). Gnidimacrin is a cyclopropanated fatty acid ester that is metabolized by hydrolysis to form a hydroxyl group. It contains ester linkages and a polyunsaturated side chain.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 774.89 g/mol
• Formula: C₄₄H₅₄O₁₂
• Purezza: Min. 95%