Harringtonine

CAS: 26833-85-2

Rif. 3D-FH15975

Informazioni sul prodotto

• Nome: Harringtonine
• Sinonimi: 3-4-Methyl-(2R)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioatecephalotaxine
• Marchio: Biosynth
• Descrizione: Harringtonine is a plant-derived alkaloid, which is isolated from the seeds of the Cephalotaxus species. It functions primarily by inhibiting protein synthesis within eukaryotic cells, targeting the elongation step of translation. Harringtonine binds to the ribosomal A-site cleft, halting the proper addition of amino acids to the growing polypeptide chain and thereby inducing apoptosis in rapidly dividing cells.

Proprietà chimiche

• Peso molecolare: 531.59 g/mol
• Formula: C₂₈H₃₇NO₉
• Purezza: Min. 95%
• Colore/Forma: White Off-White Powder
• InChI: InChI=1S/C28H37NO9/c1-26(2,32)8-9-28(33,15-22(30)35-4)25(31)38-24-21(34-3)14-27-7-5-10-29(27)11-6-17-12-19-20(37-16-36-19)13-18(17)23(24)27/h12-14,23-24,32-33H,5-11,15-16H2,1-4H3/t23-,24-,27+,28-/m1/s1
• InChI key: InChIKey=HAVJATCHLFRDHY-KSZYUSJVSA-N
• SMILES: COC(=O)C[C@](O)(CCC(C)(C)O)C(=O)O[C@@H]1C(OC)=C[C@]23CCCN2CCc2cc4c(cc2[C@H]13)OCO4