Icatibant

CAS: 130308-48-4

Rif. 3D-FI45882

Informazioni sul prodotto

• Nome: Icatibant
• Sinonimi: HOE 140D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-Tic-Oic-Arg
• Marchio: Biosynth

Descrizione

Icatibant is a 10 amino acid peptidomimetic of bradykinin and a selective antagonist to the bradykinin B2 receptor. Icabinant has been used for the treatment of attacks in patients with hereditary angioedema. Recent evidence has shown a link between dysregulated bradykinin‐mediated inflammation and acute respiratory distress syndrome (ARDS), a common complication in COVID-19 patients. Icatibant was proposed to inhibit excessive activation of the bradykinin B2 receptor during the SARS-CoV-2 infection, reducing the risk of ARDS._x000D_

Proprietà chimiche

• Peso molecolare: 1,304.52 g/mol
• Formula: C₅₉H₈₉N₁₉O₁₃S
• Purezza: Min. 95%
• Colore/Forma: Powder