5-Methoxygramine

CAS: 16620-52-3

Rif. 3D-FM52436

Informazioni sul prodotto

• Nome: 5-Methoxygramine
• Sinonimi: (5-Methoxy-1H-indol-3-ylmethyl)dimethylamine1-(5-Methoxy-1H-indol-3-yl)-N,N-dimethylmethanamine, (5-methoxy-1H-indol-3-yl)-N,N-dimethylmethanaminium, 1-(5-methoxy-1H-indol-3-yl)-N,N-dimethylmethanamine, 1H-Indole-3-methanamine, 5-methoxy-N,N-dimethyl-, 2-Dimethylaminomethyl-5-Methoxyindole, 3-Dimethylaminomethyl-5-methoxyindole, 5-Methoxy-3-(dimethylaminomethyl)indole, 5-Methoxy-N,N-dimethyl-1H-indole-3-methanamine, Indole, 3-[(dimethylamino)methyl]-5-methoxy-, N-[(5-Methoxy-1H-indol-3-yl)methyl]-N,N-dimethylamine, NSC 88885, [(5-Methoxy-1H-indol-3-yl)methyl]dimethylamine

Descrizione

5-Methoxygramine is a metabolic intermediate which is an analog of 5-hydroxytryptamine (5-HT). It has been shown to increase blood pressure and reduce the activity of the 5-HT2C receptor. This drug also has been found to inhibit the growth of some cancer cells in vitro, but it does not affect normal cells. It can be used as a tool for identifying compounds that may have similar effects. The binding affinity of 5-methoxygramine for the 5-HT2C receptor was measured by displacement experiments with 3H-spiperone. The effect of this compound on dopamine release from rat striatal slices was studied by measuring electrical activity in isolated heart preparations. The effect of this compound on leishmania infection was studied using infected mice and isolated heart preparations.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 204.27 g/mol
• Formula: C₁₂H₁₆N₂O
• Purezza: Min. 95%
• Colore/Forma: Powder
• InChI: InChI=1S/C12H16N2O/c1-14(2)8-9-7-13-12-5-4-10(15-3)6-11(9)12/h4-7,13H,8H2,1-3H3
• InChI key: InChIKey=GOERTRUXQHDLHC-UHFFFAOYSA-N
• SMILES: COc1ccc2[nH]cc(CN(C)C)c2c1