Informazioni sul prodotto
- 4-Nitrochinolin-1-Oxid
- 4-Nitrochinolin-N-oxid
- 4-Nitroquinoline 1-oxide
- 4-Nitroquinoline oxide
- 4-Nqo
- 4-nitroquinoline N-oxide
- N-oxido de 4-nitroquinolina
- N-oxyde de 4-nitroquinoleine
- Nitrochin
- Nsc 19645
- Vedi altri sinonimi
- Nitroquinolineoxide
- Quinoline, 4-nitro-, 1-oxide
- 4-nitro-1-oxo-1,8a-dihydroquinolinium
4-Nitroquinoline-N-oxide is a polymerase chain reaction (PCR) inhibitor that blocks the activity of methyltransferases, which are enzymes involved in DNA replication and repair. The mechanism of action has been shown to be due to the inhibition of the activities of these enzymes in cancer tissues. The efficacy of 4-Nitroquinoline-N-oxide has been demonstrated using an experimental model system composed of cells from Candida glabrata and other cancers, as well as a model system for carcinogenesis in vitro. This compound also shows antiinflammatory activity and can be used as a natural compound for chemotherapy. Chromatographic analysis has revealed that 4-Nitroquinoline-N-oxide is not toxic to wild type strains, but it is toxic to cancer cells with mutations in their DNA repair mechanisms.
Proprietà chimiche
Richiesta tecnica su: 3D-FN03293 4-Nitroquinoline-N-oxide
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