N-Boc-2-aminoacetaldehyde
CAS: 89711-08-0
Rif. 3D-FN158109
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Informazioni sul prodotto
- Tert-Butyl (2-Oxoethyl)Carbamate
- Carbamic acid, N-(2-oxoethyl)-, 1,1-dimethylethyl ester
N-Boc-2-aminoacetaldehyde is an aliphatic aldehyde that has been used in the synthesis of a number of bioactive molecules. It is synthesized by reacting an N-Boc amino acid with chloroform and hydrochloric acid. The reaction time is typically 2 hours at room temperature, although it can be decreased to 20 minutes if the temperature is increased to 60°C. The product can be purified using extraction or recrystallization methods. N-Boc-2-aminoacetaldehyde reacts with chloride ions to form phosphoranes, which are useful in clinical development as antimicrobial peptides. This compound also reacts with fluorine to form hydrogenated derivatives that have been shown to have neurokinin activity in animal models.