Nefopam hydrochloride

CAS: 23327-57-3

Rif. 3D-FN26174

Informazioni sul prodotto

• Nome: Nefopam hydrochloride
• Sinonimi: (+/-)-Nefopam hydrochlorideAcupan 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride, 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride, 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride (1:1), 3,4,5,6-Tetrahydro-5-Methyl-1-Phenyl-1H-2,5-Benzoxazocine Hydrochloride, 3-Methyl-7-Phenyl-6-Oxa-3-Azabicyclo[6.4.0]Dodeca-8,10,12-Triene Hydrochloride, 5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocin-5-ium chloride, Acupan, Fenazoxine, Fenazoxine hydrochloride, Nefopam HCl, R 738

Descrizione

3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride (THPP) is a drug that is used as an analgesic and anti-inflammatory agent. THPP interacts with nonsteroidal anti-inflammatory drugs (NSAIDs) to cause neuronal death. It has been shown to inhibit the plate test for prostaglandin synthesis in human erythrocytes. The disulfide bond between cysteine residues on the protein molecule is susceptible to oxidative cleavage by reactive oxygen species from reactive oxygen species such as hydrogen peroxide and lipid peroxidation products. This can lead to the formation of a thiolate ion and a sulfenic acid intermediate. THPP is also known to produce chronic oral toxicity in rats at doses of 837 mg/kg/day for two months. A chemiluminescence method was used to measure the reaction

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 289.8 g/mol
• Formula: C₁₇H₂₀ClNO
• Purezza: Min. 95%
• Colore/Forma: Powder