N-Nitroso guvacoline

CAS: 55557-02-3

Rif. 3D-FN26351

Informazioni sul prodotto

• Nome: N-Nitroso guvacoline
• Sinonimi: 1,2,5,6-Tetrahydro-1-nitroso-3-pyridinecarboxylic acid methyl esterNitrosoguvacoline
• Marchio: Biosynth
• Descrizione: N-Nitroso guvacoline is a nitrosated guvacoline analog that is used to induce cancer in animals and as an experimental tool for studying the role of acetylcholine in lung cancer. N-Nitroso guvacoline has been shown to inhibit the growth of bacteria such as typhimurium and nadph-cytochrome p450 in the presence of fatty acids, suggesting that it may be genotoxic. The carcinogenic effects of N-nitrosoguvacolin were studied using Sprague-Dawley rats exposed to this agent by inhalation. The rats were found to have increased levels of urinary nitrite and nitrate, which are products from the metabolism of N-nitrosoguvacolin.

Proprietà chimiche

• Peso molecolare: 170.17 g/mol
• Formula: C₇H₁₀N₂O₃
• Purezza: Min. 95%
• InChI: InChI=1S/C7H10N2O3/c1-12-7(10)6-3-2-4-9(5-6)8-11/h3H,2,4-5H2,1H3
• InChI key: InChIKey=NXEUEKXJAAVKCT-UHFFFAOYSA-N
• SMILES: COC(=O)C1=CCCN(N=O)C1