Oxyberberin

CAS: 549-21-3

Rif. 3D-FO65468

Informazioni sul prodotto

• Nome: Oxyberberin
• Sinonimi: Berlambine, 5,6-Dihydro-9,10-dimethoxy-8H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-8-one, 8-Oxoberberine, 8-Oxyberberine, 8H-1,3-benzodioxolo[5,6-a]benzo[g]quinolizin-8-one, 5,6-dihydro-9,10-dimethoxy-, 8H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-8-one, 5,6-dihydro-9,10-dimethoxy-, Berberin-8-one, Berbin-8-one, 13,13a-didehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, Jkl 1073A, NSC 93138, Oxyberberine

Descrizione

Oxyberberin is a natural compound that has been used in traditional Chinese medicine. It has been shown to have significant cytotoxicity against cancer cell lines and is an effective hypoglycemic agent. Oxyberberin has also been found to be useful in treating liver steatosis, bowel disease, and other symptoms related to metabolic disorders. The molecular docking analysis of oxyberberin with acetate extract showed a high degree of similarity with the binding of chloroperbenzoic acid, indicating that oxyberberin may be metabolized by the same pathway as chloroperbenzoic acid. It is hypothesized that oxyberberin can be used as a novel therapeutic agent for congestive heart failure by inhibiting the production of reactive oxygen species that are associated with cardiac hypertrophy and fibrosis.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 351.35 g/mol
• Formula: C₂₀H₁₇NO₅
• Purezza: Min. 98 Area-%
• Colore/Forma: Powder
• InChI: InChI=1S/C20H17NO5/c1-23-15-4-3-12-7-14-13-9-17-16(25-10-26-17)8-11(13)5-6-21(14)20(22)18(12)19(15)24-2/h3-4,7-9H,5-6,10H2,1-2H3
• InChI key: InChIKey=ZHYQCBCBTQWPLC-UHFFFAOYSA-N
• SMILES: COc1ccc2cc3n(c(=O)c2c1OC)CCc1cc2c(cc1-3)OCO2