Precholecalciferol

CAS: 1173-13-3

Rif. 3D-FP159099

Informazioni sul prodotto

• Nome: Precholecalciferol
• Sinonimi: (1S)-3-[(1Z)-2-[(1R,3aR,7aR)-1-[(1R)-1,5-Dimethylhexyl]-2,3,3a,6,7,7a-hexahydro-7a-methyl-1H-inden-4-yl]ethenyl]-4-methyl-3-cyclohexen-1-ol, (1S)-3-[2-[(1R,3aR,7aR)-1-[(1R)-1,5-dimethylhexyl]-7a-methyl-1,2,3,3a,6,7-hexahydroinden-4-yl]vinyl]-4-methyl-cyclohex-3-en-1-ol, (3S,6Z,14β)-9,10-secocholesta-5(10),6,8-trien-3-ol, (3beta,6Z)-9,10-Secocholesta-5(10),6,8-trien-3-ol, 3-Cyclohexen-1-ol, 3-[(1Z)-2-[(1R,3aR,7aR)-1-[(1R)-1,5-dimethylhexyl]-2,3,3a,6,7,7a-hexahydro-7a-methyl-1H-inden-4-yl]ethenyl]-4-methyl-, (1S)-, 9,10-Secocholesta-5(10),6,8-trien-3-ol, (3β,6Z)-, 9,10-Secocholesta-5(10),6,8-trien-3β-ol, Precalciferol, Precalciferol₃, Previtamin D, Previtamin D(3), Previtamin D₃

Descrizione

Precholecalciferol is a vitamin D analog that has been shown to be active in the target tissue. It is used for the treatment of chronic kidney disease and autoimmune diseases, including multiple sclerosis. The activated form of this drug is converted to calcitriol by hydroxylation, which is then metabolized by the liver. This form of the drug can also be converted by epoxide hydrolase to 25-hydroxycholecalciferol, which can be further metabolized by cytochrome P450 enzymes to 1,25-dihydroxycholecalciferol (1,25-(OH)2D3). This form of the drug can bind to nuclear receptors and activate gene transcription. Precholecalciferol has been shown to activate growth factors such as insulin-like growth factor-I and platelet-derived growth factor, which may contribute to its role in treating autoimmune diseases.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 384.64 g/mol
• Formula: C₂₇H₄₄O
• Purezza: Min. 95%
• Colore/Forma: Powder
• InChI: InChI=1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h10,12-13,19,21,24-26,28H,6-9,11,14-18H2,1-5H3/b13-12-/t21-,24+,25?,26+,27-/m1/s1
• InChI key: InChIKey=YUGCAAVRZWBXEQ-OELPRXOWSA-N
• SMILES: CC1=C(/C=C\C2=CCC[C@]3(C)C([C@H](C)CCCC(C)C)CC[C@@H]23)C[C@@H](O)CC1