N2-Phenoxyacetyl guanine

CAS: 144782-23-0

Rif. 3D-FP26887

Informazioni sul prodotto

• Nome: N2-Phenoxyacetyl guanine
• Sinonimi: N-(6,7-Dihydro-6-oxo-1H-purin-2-yl)-2-phenoxy-acetamide, N-(6-oxo-3,7-dihydropurin-2-yl)-2-phenoxy-acetamide

Descrizione

N2-Phenoxyacetyl guanine is a labile nucleoside that can be synthesized by the aminoacylation of guanosine with phenoxyacetic acid. It has been shown to have an important role in oxidative DNA damage, which may lead to mutagenesis and cancer. N2-Phenoxyacetyl guanine is stereoselective and binds preferentially to the GGC sequence, and it is also aminopropylated at its 2′ position. This nucleoside is not ionizing but can be degraded by radiation or enzymes such as deaminases.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 285.26 g/mol
• Formula: C₁₃H₁₁N₅O₃
• Purezza: Min. 95%
• InChI: InChI=1S/C13H11N5O3/c19-9(6-21-8-4-2-1-3-5-8)16-13-17-11-10(12(20)18-13)14-7-15-11/h1-5,7H,6H2,(H3,14,15,16,17,18,19,20)
• InChI key: InChIKey=VXZMETBWWUIXNK-UHFFFAOYSA-N
• SMILES: O=C(COc1ccccc1)Nc1nc2nc[nH]c2c(=O)[nH]1