Pentetic acid

CAS: 67-43-6

Rif. 3D-FP29951

Informazioni sul prodotto

• Nome: Pentetic acid
• Sinonimi: DTPADiethylenetriaminepentaacetic acid
• Marchio: Biosynth

Descrizione

Pentetic acid, also known as DTPA, is an organic compound that act as metal chelator or radioligand for diagnosis applications. It binds to prostate receptors and has been shown to have tumor treatment properties by inhibiting prostate cancer cell growth and inducing apoptosis. DTPA has a high affinity to radiactive metals (lutetium (Lu-117), gallium (Ga-67), indium (In-111), yttrium (Y-90), gadolinium (Gd(III)) and yttrium (Y(III)) which makes the conjugate being really useful for MRI contrast imaging and radiolabeling. DTPA, as similar compounds like, NOTA, DOTA and TETA, is used as radionuclide when binding to integrin receptors on the surface of cancer cells. Pentetic acid has been shown to have anti-tumour effects against squamous carcinoma cells in vitro and to inhibit the activity of enzymes involved in inflammation, such as cyclooxygenase-2 (COX-2), lipoxygenase, and phospholipase A2. Pentetic acid also inhibits the synthesis of prostaglandins and leukotrienes.

Proprietà chimiche

• Peso molecolare: 393.35 g/mol
• Formula: C₁₄H₂₃N₃O₁₀
• Purezza: Min 98%
• Colore/Forma: Powder