3-Phenoxybenzoic acid

CAS: 3739-38-6

Rif. 3D-FP59793

Informazioni sul prodotto

• Nome: 3-Phenoxybenzoic acid
• Sinonimi: 3-Carboxydiphenyl ether, 3-Pba, 3-Phenoxybenzoate, 4,4-Dihydroxybenzophenone/4,4-Dihydroxybenzophenone, Benzoic acid, 3-phenoxy-, Benzoic acid, m-phenoxy-, M-Phenoxybenzoic acid, m-(Phenyloxy)benzoic acid

Descrizione

3-Phenoxybenzoic acid is a metabolite of nonsteroidal anti-inflammatory drugs (NSAIDs) and pyrethroid insecticides. It is an inhibitor of the enzyme matrix metalloproteinases, which are involved in the degradation of collagen. 3-Phenoxybenzoic acid was used as a model system to study the effects of NSAIDs on urinary excretion rates and to identify biomarkers for NSAID use. The metabolite can be detected in urine after ingestion by using analytical methods such as preparative high performance liquid chromatography or electrochemical impedance spectroscopy. 3-Phenoxybenzoic acid is also present in cells from human HL-60 cells and has been shown to inhibit the growth of human leukemia cells by interfering with protein synthesis.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 214.22 g/mol
• Formula: C₁₃H₁₀O₃
• Purezza: Min. 95%
• Colore/Forma: Powder
• InChI: InChI=1S/C13H10O3/c14-13(15)10-5-4-8-12(9-10)16-11-6-2-1-3-7-11/h1-9H,(H,14,15)
• InChI key: InChIKey=NXTDJHZGHOFSQG-UHFFFAOYSA-N
• SMILES: O=C(O)c1cccc(Oc2ccccc2)c1