2-(4-Bromophenyl)-1H-indole

Rif. 3D-GAA12749

Informazioni sul prodotto

• Nome: 2-(4-Bromophenyl)-1H-indole
• Marchio: Biosynth
• Descrizione: 2-(4-Bromophenyl)-1H-indole is a ligand, which binds to the benzodiazepine receptor in the central nervous system. 2-(4-Bromophenyl)-1H-indole is synthesised and tested for its affinity for this receptor. The uptake of 2-(4-bromophenyl)-1H-indole into rat brain tissue is studied using autoradiography. It is found that 2-(4-bromophenyl)-1H-indole has high affinity for the benzodiazepine binding site on rat brain membranes and modulates the activity of GABA receptors, which causes sedation. The effects of halogens on 2-(4-bromophenyl)-1H-indole are investigated by measuring their effect on its uptake into rat brain tissue. Flumazenil, an antagonist of benzodiazepine receptors, blocks the effects of 2-(4-bromophenyl)-1H

Proprietà chimiche

• Peso molecolare: 272.15 g/mol
• Formula: C₁₄H₁₀BrN
• Purezza: Min. 95%