Informazioni sul prodotto
- (1S)-1-(7-amino-2H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol
- (1S)-1-C-(7-Amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-<span class="text-smallcaps">D</span>-ribitol
- (5R)-5-(7-amino-2H-pyrazolo[4,3-d]pyrimidin-3-yl)-2,5-anhydro-D-ribitol
- 1-(7-amino-2H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydropentitol
- 1H-Pyrazolo(4,3-d)pyrimidine, 7-amino-3-beta-D-ribofuranosyl-
- 1H-Pyrazolo[4,3-d]pyrimidine, 7-amino-3-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- 1H-Pyrazolo[4,3-d]pyrimidine, <span class="text-smallcaps">D</span>-ribitol deriv.
- 7-Amino-3-beta-D-ribofuranosyl-1H-pyrazolo(4,3-d)pyrimidine
- 8-Aza-9-deazaadenosine
- <span class="text-smallcaps">D</span>-Ribitol, 1-C-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-, (1S)-
- Vedi altri sinonimi
- Brn 0624229
- D-Ribitol, 1-C-(7-amino-1H-pyrazolo(4,3-d)pyrimidin-3-yl)- 1,4-anhydro-, (S)- (9CI)
- Formycin
- Nsc 102811
- (1S)-1-C-(7-Amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol
- 1H-Pyrazolo[4,3-d]pyrimidine, D-ribitol deriv.
- Formycin A
- 1H-Pyrazolo[4,3-d]pyrimidine, 7-amino-3-β-D-ribofuranosyl-
- D-Ribitol, 1-C-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-, (1S)-
Formycin A is an equilibrative nucleoside with inhibitory properties. It has been shown to be active against infectious diseases such as leishmania, trypanosomes and chlamydia. Formycin A binds to the pyrazole ring of a protein called DCTPase, which is involved in the metabolism of purines and pyrimidines. This binding blocks the enzyme's activity and leads to the accumulation of cytosolic Ca2+, which triggers apoptosis. The effect of formycin A on this protein is reversible, so it can be used as a vaccine adjuvant or in combination with other antibiotics. Formycin A also has biochemical properties that allow it to act as an inhibitor for other proteins that are involved in DNA synthesis and rRNA transcription.
Proprietà chimiche
Richiesta tecnica su: 3D-GAA74212 Formycin A
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