AZD3463
CAS:
Rif. 3D-GEC96220
Informazioni sul prodotto
Nome:AZD3463
Marchio:Biosynth
Descrizione:AZD3463 is a small molecule that inhibits the ubiquitin proteasome. It has been shown to be effective in vivo, as well as in vitro, for the treatment of cancer. AZD3463 binds to the carbonyl group on the protein substrate and inhibits the activity of the drug-metabolizing enzyme, adp-ribose hydrolase. This inhibition prevents degradative processes from occurring within cells and leads to an increase in autophagy. AZD3463 also inhibits epidermal growth factor receptor (EGFR) signaling pathways and activates tumor suppressor genes such as p53 and p21. Pharmacokinetic properties have been studied in mice, rats, and cynomolgus monkeys.
Avviso:I nostri prodotti sono destinati esclusivamente ad uso di laboratorio. Per qualsiasi altro utilizzo, vi preghiamo di contattarci.
Proprietà chimiche
Peso molecolare:448.95 g/mol
Formula:C24H25ClN6O
Purezza:Min. 95%