Aztreonam impurity D
CAS: 102579-59-9
Rif. 3D-IA167738
1mg | 346,00 € | ||
2mg | 488,00 € | ||
5mg | 818,00 € | ||
10mg | 1.167,00 € | ||
25mg | 2.228,00 € |
Informazioni sul prodotto
- Desulfo aztreonam
Aztreonam impurity D is a metabolite of aztreonam. Aztreonam impurity D is an impurity standard for the pharmacopoeia and API industry, as well as for drug development and research. It has been shown that this compound inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Aztreonam impurity D also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.
Proprietà chimiche
Richiesta tecnica su: 3D-IA167738 Aztreonam impurity D
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