Informazioni sul prodotto
- Urea, N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-
- 1-(3-Chloro-4-methylphenyl)-3-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)urea
CC-885 is a pharmacologic agent that inhibits the ubiquitin ligases, which are enzymes that catalyze the transfer of ubiquitin to proteins. CC-885 has been shown to increase the levels of ubiquitinated proteins in cells and to inhibit their degradation by the proteasome. This drug has been shown to alter translation and cellular response pathways, leading to a clinical response in patients with chronic lymphocytic leukemia (CLL). It also acts as an immunomodulatory drug for lymphocytic leukemia, inhibiting transcriptional activation of NF-κB and NFAT in T cells. CC-885 is being developed for use as a cancer therapeutic agent. The mechanism of action is not fully understood, but it may be due to its ability to inhibit DNA replication or induce apoptosis.
Proprietà chimiche
Richiesta tecnica su: 3D-KQB10007 CC-885
Se si desidera richiedere un preventivo o effettuare un ordine, si prega invece di aggiungere i prodotti desiderati al carrello e poi richiedere un preventivo o un ordine dal carrello. È più veloce, più economico, e potrà beneficiare degli sconti disponibili e di altri vantaggi.
