Cereblon modulator 1
CAS:
Rif. 3D-KZC87551
Informazioni sul prodotto
Nome:Cereblon modulator 1
Marchio:Biosynth
Descrizione:Cereblon modulator 1 is a prodrug that binds to the E3 ubiquitin ligase, Cereblon, and blocks its activity. This drug is being studied for use in hematologic malignancies. Cereblon modulator 1 has been shown to inhibit the proliferation of myelodysplastic cells by inducing c-myc protein degradation and inhibiting IL-1 receptor activation. The drug also inhibits the growth of cancer cells by blocking the Tautomerase function of Cereblon, thereby preventing the conversion of inactive proteins into active proteins. Cereblon modulator 1's linker is heterocyclic, which is likely responsible for its antagonist effect on IL-1 receptor activation.
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Proprietà chimiche
Peso molecolare:461.8 g/mol
Formula:C22H18ClF2N3O4
Purezza:Min. 95%