
Leptomycin A
CAS:
Rif. 3D-MDA08136

Informazioni sul prodotto
Nome:Leptomycin A
Marchio:Biosynth
Descrizione:Leptomycin A is a Streptomyces-produced inhibitor, which is derived from the bacterium Streptomyces spiroverticillatus. It functions by specifically binding to and inhibiting the CRM1 (exportin 1), a nuclear export receptor. This action blocks the nuclear export of proteins that contain a leucine-rich nuclear export signal (NES), thereby leading to their accumulation within the nucleus. The inhibition of CRM1 disrupts various cellular processes, including cell cycle regulation and signal transduction pathways.
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Proprietà chimiche
Peso molecolare:526.7 g/mol
Formula:C32H46O6
Purezza:Min. 95%