5-Hydroxypyrazine-2-carboxamide
CAS:
Rif. 3D-NAA92496
Informazioni sul prodotto
Nome:5-Hydroxypyrazine-2-carboxamide
Marchio:Biosynth
Descrizione:5-Hydroxypyrazine-2-carboxamide is a prodrug of pyrazinamide, an anti-tuberculosis drug. It is metabolized to pyrazinoic acid in the liver and excreted in the urine. The concentration of 5-hydroxypyrazine-2-carboxamide in the blood plasma is very low and no significant accumulation has been observed. In experiments with rats, 5-hydroxypyrazine-2-carboxamide was shown to be well tolerated and did not produce any adverse effects at doses up to 500 mg/kg orally. It also effectively inhibited bacterial growth in vitro and showed good activity against Mycobacterium tuberculosis and Mycobacterium avium complex.5-Hydroxypyrazine-2-carboxamide is used for the treatment of tuberculosis in pediatric patients who cannot tolerate other antitubercular drugs or who have failed to respond satisfactorily to other
Avviso:I nostri prodotti sono destinati esclusivamente ad uso di laboratorio. Per qualsiasi altro utilizzo, vi preghiamo di contattarci.
Proprietà chimiche
Peso molecolare:139.11 g/mol
Formula:C5H5N3O2
Purezza:Min. 95%
Colore/Forma:Powder