N4-Benzoyl-1-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)cytosine

Rif. 3D-NB08465

Informazioni sul prodotto

• Nome: N4-Benzoyl-1-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)cytosine
• Marchio: Biosynth
• Descrizione: N4-Benzoyl-1-(2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)cytosine is a nucleoside analogue that inhibits HIV reverse transcriptase. It is a monophosphate and a diphosphate, which are activated by phosphorylation to form the active triphosphate. N4-Benzoyl-1-(2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)cytosine has been shown to be an antiviral and anticancer agent. This compound has been modified with an aromatic benzoyl group at position 4 of the sugar moiety in order to block the interaction with the viral polymerase.

Proprietà chimiche

• Peso molecolare: 349.32 g/mol
• Formula: C₁₆H₁₆FN₃O₅
• Purezza: Min. 95%
• InChI: InChI=1S/C16H16FN3O5/c17-12-13(22)10(8-21)25-15(12)20-7-6-11(19-16(20)24)18-14(23)9-4-2-1-3-5-9/h1-7,10,12-13,15,21-22H,8H2,(H,18,19,23,24)/t10-,12?,13+,15-/m1/s1
• InChI key: InChIKey=RHCOKFXBQWNMHE-INHPVMQOSA-N
• SMILES: O=C(Nc1ccn([C@@H]2O[C@H](CO)[C@H](O)C2F)c(=O)n1)c1ccccc1