LY 2087101
CAS: 913186-74-0
Rif. 3D-NLB18674
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Informazioni sul prodotto
LY 2087101 is a selective α7 nicotinic acetylcholine receptor (α7NAChR) agonist that has been shown to have therapeutic potential in the treatment of inflammatory diseases, such as rheumatoid arthritis. LY 2087101 binds to the α7NAChR and stimulates it, leading to the release of dopamine. This drug has been found to be beneficial in alleviating psychotic disorders and may be useful in treating nicotine addiction. LY 2087101 also blocks cation channels that are associated with pain and inflammation. This drug has been shown to selectively activate specific types of α7 NAChRs, which can be used as a pharmacological probe for studying their role in physiological processes. LY 2087101 has good pharmacokinetic properties and an oral bioavailability of >90%. It is eliminated by hepatic metabolism via cytochrome P450 enzymes, primarily CYP3A4, with a half-life of approximately 20 hours.
Proprietà chimiche
Richiesta tecnica su: 3D-NLB18674 LY 2087101
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