Informazioni sul prodotto
- Gb3α-D-Gal-(1→4)-β-D-Gal-(1→4)-β-D-Glc-1→O-ceramideCeramide trihexosides
- 71965-57-6
- Cd 77
- Ceramide trihexoside
- Ceramide, 1-O-(O-α-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-(1→4)-O-β-<smallcap>D</smallcap>-galactopyranosyl-(1→4)-β-<smallcap>D</span>-glucopyranosyl)-
- Fabry glycolipid
- Ganglioside G<sub>L3</sub>
- Ganglioside Gb<sub>3</sub>
- Gb<sub>3</sub>
- Gb<sub>3</sub>Cer
- Vedi altri sinonimi
- Globo-N-triaosylceramide
- Globotriglycosylceramide
- Globotriosylceramide
- Shiga toxin receptor
- Trihexosylceramide
- Ceramide, 1-O-(O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl)-
It is one of the few clusters of differentiation that is not a protein and structurally contains a galactose moiety linked α to lactosylceramide. Defects in the enzyme α-galactosidase lead to the buildup of globotriaosylceramide, causing Fabry's disease. The pharmaceutical drug migalastat enhances the function of α-galactosidase and is used to treat Fabry's. Globotriaosylceramide is also one of the targets of Shiga toxin, which is responsible for pathogenicity of enterohemorrhagic E. coli.
Proprietà chimiche
Richiesta tecnica su: 3D-OG45939 Globotriaosylceramide
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