GD1a-Oligosaccharide

CAS: 71494-27-4

Rif. 3D-OO35336

Informazioni sul prodotto

• Nome: GD1a-Oligosaccharide
• Sinonimi: GD1aSaccharide
• Marchio: Biosynth
• Descrizione: GD1a oligosaccharide is the carbohydrate moiety from the disialylated glycosphingolipid GD1a of the a-series (shown in the sodium form), a major ganglioside found in neuronal and glial membranes. GD1a oligosaccharide has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acids linked α2,3/α2,8 to the inner galactose residue, α2,3 to the outer galactose residue (Ledeen, 2009). GD1a ganglioside interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GD1a ganglioside plays a role in viral infection as it is a receptor for viral glycoproteins in rotavirus and paramyxovirus 1. The hexasaccharide GD1a moiety was also found on a glycoprotein that acts as a receptor for adenovirus type 37. Additionally, GD1a ganglioside interacts with botulinum neurotoxin (BoNT) and is crucial for its entry into cells (Kolter, 2012).

Proprietà chimiche

• Peso molecolare: 1,290.14 g/mol
• Formula: C₄₈H₇₉N₃O₃₇
• Purezza: Min. 95%
• Colore/Forma: Powder