GD2-Oligosaccharide-sp-biotin

Rif. 3D-OO71835

Informazioni sul prodotto

• Nome: GD2-Oligosaccharide-sp-biotin

Descrizione

The structure of GD2-oligosaccharide-sp-biotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) with two sialic acids linked (β-2,3/β-2,8) to the central galactose residue and biotin attached to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors, including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, it has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 1,695.61 g/mol
• Formula: C₆₅H₁₀₄N₁₀O₃₇S·2Na
• Purezza: One Spot
• Colore/Forma: White Powder