N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite

CAS: 110782-31-5

Rif. 3D-PB08471

Informazioni sul prodotto

• Nome: N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite
• Sinonimi: N6-Benzoyl-5'-O-DMT-2'-O-methyl-D-adenosine 3'-CE phosphoramidite
• Marchio: Biosynth
• Descrizione: N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite is a nucleoside phosphoramidite used as a building block in the chemical synthesis of oligonucleotides containing a 2’-O-methyl adenosine nucleoside unit. The use of a chemical synthesis rather than an enzymatic one allows oligonucleotides of a desired sequence to be produced. 3’-Cyanoethyl phosphoramidites are typically used by substitution of the di-isopropylamine group with an appropriate alcohol in the presence of an azole catalyst. Oligonucleotides containing 2'-O-methylribonucleoside units have shown site-specific cleavage with E. coli RNase H, either at a hairpin loop or at a stem region.

Proprietà chimiche

• Peso molecolare: 887.98 g/mol
• Formula: C₄₈H₅₄N₇O₈P
• Purezza: Min. 98 Area-%
• Colore/Forma: White Off-White Powder