X-34
CAS:
Rif. 3D-QIA29498
Informazioni sul prodotto
Nome:X-34
Marchio:Biosynth
Descrizione:X-34 is a p-glycoprotein (p-gp) inhibitor that is used to prevent the accumulation of toxic drugs in certain tissues, such as the brain. X-34 binds to the drug transporter protein, inhibiting its function. This leads to an increase in the concentration of the drug at target sites and reduces toxicity. X-34 has been shown to be effective against resistant mutants of p-gp substrates, such as paclitaxel and vincristine. The conformational properties of X-34 have been determined by x-ray diffraction data and molecular modelling techniques. The hydroxyl group on the phenyl ring has been shown to interact with other compounds, which may lead to adverse reactions when combined with other drugs. X-34 inhibits transcription and replication by binding to DNA polymerase II or RNA polymerase II. This binding prevents transcription and replication by preventing DNA synthesis or RNA synthesis, respectively.
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Proprietà chimiche
Peso molecolare:402.4 g/mol
Formula:C24H18O6
Purezza:Min. 95%