2-(4-Bromophenyl)propan-2-amine

CAS: 17797-12-5

Rif. 3D-SAA79712

Informazioni sul prodotto

• Nome: 2-(4-Bromophenyl)propan-2-amine
• Marchio: Biosynth
• Descrizione: 2-(4-Bromophenyl)propan-2-amine (BPAP) is an analogue of the antihistamine diphenhydramine. The BPAP analogues are selective for protein kinases, such as vegfr-2, cyclin, and cdk1. VEGFR-2 is a receptor tyrosine kinase that is activated by vascular endothelial growth factor and plays a role in angiogenesis. Cyclin is a serine/threonine protein kinase that regulates the cell cycle and CDK1 regulates the progression from G1 to S phase. In vivo efficacy studies have shown that BPAP inhibits these three kinases with an IC50 value of less than 1 μM in human tumor cells.

Proprietà chimiche

• Peso molecolare: 214.1 g/mol
• Formula: C₉H₁₂BrN
• Purezza: Min. 95%